Dynamic Resting-State Functional Connectivity in Major Depression
نویسندگان
چکیده
منابع مشابه
Abnormal amygdala resting-state functional connectivity in adolescent depression.
IMPORTANCE Major depressive disorder (MDD) frequently emerges during adolescence and can lead to persistent illness, disability, and suicide. The maturational changes that take place in the brain during adolescence underscore the importance of examining neurobiological mechanisms during this time of early illness. However, neural mechanisms of depression in adolescents have been understudied. R...
متن کاملResting-State Functional Connectivity Abnormalities in Adolescent Depression
Article history: Received 28 February 2017 Accepted 28 February 2017 Available online 3 March 2017 (Cullen et al., 2014). Chattopadhyay and co-workers examined differences in restingstate functional connectivity (rsFC) between adolescent patients with MDD andmatched healthy controls as well as changes in rsFC following cognitive behavioral therapy (CBT) (Chattopadhyay et al., 2017-in this issue...
متن کاملResting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus.
BACKGROUND Positron emission tomography (PET) studies of major depression have revealed resting-state abnormalities in the prefrontal and cingulate cortices. Recently, fMRI has been adapted to examine connectivity within a specific resting-state neural network--the default-mode network--that includes medial prefrontal and anterior cingulate cortices. The goal of this study was to examine restin...
متن کاملAltered resting state functional connectivity of fear and reward circuitry in comorbid PTSD and major depression.
BACKGROUND Individuals with comorbid posttraumatic stress disorder and major depressive disorder (PTSD-MDD) often exhibit greater functional impairment and poorer treatment response than individuals with PTSD alone. Research has not determined whether PTSD-MDD is associated with different network connectivity abnormalities than PTSD alone. METHODS We used functional magnetic resonance imaging...
متن کاملWhole Brain Resting-State Analysis Reveals Decreased Functional Connectivity in Major Depression
Recently, both increases and decreases in resting-state functional connectivity have been found in major depression. However, these studies only assessed functional connectivity within a specific network or between a few regions of interest, while comorbidity and use of medication was not always controlled for. Therefore, the aim of the current study was to investigate whole-brain functional co...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2015
ISSN: 0893-133X,1740-634X
DOI: 10.1038/npp.2015.352